Protein Info for KEDOAH_04860 in Escherichia coli ECRC99

Name: yejO
Annotation: autotransporter YejO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 863 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF16168: AIDA" amino acids 184 to 245 (62 residues), 84.8 bits, see alignment 5.2e-28 amino acids 257 to 315 (59 residues), 76.6 bits, see alignment 1.8e-25 TIGR04415: autotransporter passenger strand-loop-strand repeat" amino acids 198 to 234 (37 residues), 26.9 bits, see alignment (E = 3.7e-10) amino acids 217 to 249 (33 residues), 22.4 bits, see alignment (E = 9.6e-09) PF03212: Pertactin" amino acids 431 to 555 (125 residues), 151.4 bits, see alignment E=1.6e-48 TIGR01414: outer membrane autotransporter barrel domain" amino acids 456 to 863 (408 residues), 373.2 bits, see alignment E=1.9e-115 PF03797: Autotransporter" amino acids 602 to 841 (240 residues), 154.2 bits, see alignment E=8.5e-49

Best Hits

Swiss-Prot: 97% identical to YEJO_ECOLI: Putative uncharacterized outer membrane protein YejO (yejO) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eok:G2583_2733)

Predicted SEED Role

"Type I secretion system ATPase, LssB family LapB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (863 amino acids)

>KEDOAH_04860 autotransporter YejO (Escherichia coli ECRC99)
MHQSGSVSLCRSAISVLVATALYSPIALASTVEYGETVDGVVLEKDIQLVYGTANNTKIN
PGGEQHIKEFGISSNTEINGGYQYIEMNGTAEYSVLNDGYQIVQMGGAANQTTLNNGVLQ
VYGAANDPTIKGGRLIVEKDGITVLAAIEKGGLLEVKEGGLAIAVDQKAGGAIKASTRVM
EVFGTNRLGQFEIKNGIANNMLLENGGSLRVEENDFAYNTTVDSGGLLEVMDGGTATGVD
KKAGGKLIVSTNALEVSGTNSKGQFSIKDGVSKNYELDDGSGLIVMEDTQAIDTILDEHA
TMQSLGKDTGTRVQANAVYDLGRSDQNGSITYSSKAISENMVINNGRANVWAGTMVNVSV
RGNDGILEVMKPQINYAPAMLVGKVVVSEGASLRTHGAVDTSKADVSLENSAWTIIADIT
TTNQNTRLNLANLAMSGANVIMMDESVTRSSVTASAENFTTLTTNTLSGNGNFYMRTDMA
NHQSDQLNVTGQATGDFKIFVTDTGASPAAGDSLTLVTTGGGDAAFTLGNAGGVVDIGTY
EYTLLDNGNHSWSLAENRAQITPSTTDVLNMAAAQPLVFDAELDTVRERLGSVKGVSYDT
AMWSSAINTRNNVTTDAGAGFEQTLTGLTLGIDSRFSREESSTIRGLFFGYSHSDIGFDR
GGKGNVDSYTLGAYAGWEHQNGAYVDGVVKVDRFANTIHGKMSNGATAFGDYNSNGAGAH
VESGFRWVDGLWSVRPYLAFTGFTTDGQDYTLSNGMRADVGNTRILRAEAGTAVSYHMDL
QNGTTLEPWLKAAVRQEYADSNQVKVNDDGKFNNDVAGTRGVYQAGIRSSFTPTLSGHLS
VSYGNGAGVESPWNTQAGVVWTF