Protein Info for JDDGAC_18155 in Escherichia coli ECRC98

Name: wzyE
Annotation: ECA oligosaccharide polymerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 36 to 58 (23 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 115 to 137 (23 residues), see Phobius details amino acids 157 to 175 (19 residues), see Phobius details amino acids 182 to 199 (18 residues), see Phobius details amino acids 205 to 223 (19 residues), see Phobius details amino acids 227 to 245 (19 residues), see Phobius details amino acids 337 to 361 (25 residues), see Phobius details amino acids 380 to 398 (19 residues), see Phobius details amino acids 409 to 430 (22 residues), see Phobius details PF06899: WzyE" amino acids 1 to 447 (447 residues), 908.8 bits, see alignment E=3.3e-278

Best Hits

Swiss-Prot: 100% identical to WZYE_ECO57: Probable ECA polymerase (wzyE) from Escherichia coli O157:H7

KEGG orthology group: K02853, 4-alpha-L-fucosyltransferase [EC: 2.4.1.-] (inferred from 100% identity to eco:b3793)

Predicted SEED Role

"Putative ECA polymerase"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-

Use Curated BLAST to search for 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>JDDGAC_18155 ECA oligosaccharide polymerase (Escherichia coli ECRC98)
MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFR
FDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVIL
MGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSK
AWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGM
FWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVF
IPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLI
IKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACL
MIAKLLYWLFESAGLIHKRTKSSLRTQVEG