Protein Info for IAI46_20385 in Serratia liquefaciens MT49

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 transmembrane" amino acids 48 to 71 (24 residues), see Phobius details amino acids 85 to 107 (23 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 174 to 197 (24 residues), see Phobius details amino acids 203 to 224 (22 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 319 to 338 (20 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 373 to 397 (25 residues), see Phobius details amino acids 410 to 433 (24 residues), see Phobius details amino acids 439 to 461 (23 residues), see Phobius details PF07690: MFS_1" amino acids 55 to 231 (177 residues), 109.3 bits, see alignment E=2e-35 amino acids 288 to 463 (176 residues), 58.9 bits, see alignment E=4.2e-20 PF00083: Sugar_tr" amino acids 62 to 411 (350 residues), 101.9 bits, see alignment E=4.1e-33

Best Hits

KEGG orthology group: K08195, MFS transporter, AAHS family, 4-hydroxybenzoate transporter (inferred from 46% identity to bch:Bcen2424_0819)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (469 amino acids)

>IAI46_20385 MFS transporter (Serratia liquefaciens MT49)
MTEDKKYILLKNIFYSHKKGYPVSMSANEGMQSIQEMVDSTGTRRGQVLLLTMCALCLLC
DGFDIQAMGYAAPAIRDAWSLETAVLGPVFSAGLAGIAIGAFALGWLADRIGRRPSIISA
TLIFGVFTLCSAFAQNVNQLMAFRFLAGVALGGVMPNCIALVVEYSPLRQRATYITAITC
FFAIGGGLGGVTAALLIPLVGWQAIFILGGLLPIILAISMWAYLPESAQWMLRCGKGETA
IRSTLRKVFPEQQAMSVDLSNSHIGMQRAKATVVDLFRDNRAAFTLLLWLVNFMNLIDLY
FLANWLPTLIKDAGLSLEIANLATGALQFGGVLGTLALGRLIDKFGAYSVLITGFSIAAL
SIAAIGFEPKNLLMLFSSVFVTGVFVVGGMPGVNALAAGGYPTFLRSTGLGWGLGIGRGA
SMLGPLLGAALIARHWMAYDLLLLAAVPAVVSALAIGGMWLQKRESHYD