Protein Info for IAI46_12630 in Serratia liquefaciens MT49

Annotation: D-serine transporter DsdX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 30 to 49 (20 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 99 to 130 (32 residues), see Phobius details amino acids 140 to 163 (24 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 260 to 283 (24 residues), see Phobius details amino acids 302 to 322 (21 residues), see Phobius details amino acids 343 to 373 (31 residues), see Phobius details amino acids 385 to 408 (24 residues), see Phobius details amino acids 420 to 444 (25 residues), see Phobius details PF02447: GntP_permease" amino acids 11 to 443 (433 residues), 528.5 bits, see alignment E=6.5e-163 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 12 to 445 (434 residues), 548.5 bits, see alignment E=6.6e-169

Best Hits

Swiss-Prot: 85% identical to DSDX_ECOLI: D-serine transporter DsdX (dsdX) from Escherichia coli (strain K12)

KEGG orthology group: K13629, D-serine transporter (inferred from 95% identity to spe:Spro_2450)

Predicted SEED Role

"D-serine permease DsdX" in subsystem Glycine and Serine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>IAI46_12630 D-serine transporter DsdX (Serratia liquefaciens MT49)
MDSHIWVAGTLIASIALIILTIVKFKFHPFLALLLASFFVGGMMGMGPIDMVNAIENGIG
STLGFLAAVIGLGTILGKMMEVSGAAERIGIALQRCRWLSVDVIMVLVGLVCGITLFVEV
GVVLLIPLAFSIARKTGTSLLKLAIPLCTALMAVHCVVPPHPAALFVTNKLGADVGTVIV
YGLLVGLTASLVGGPLFLKILGKRLPFKPVPPEFSNLTVREEHELPSLRATLFTVLLPIV
LMLVKTVAELNLAKEGRLFGLMEFIGNPIIAMFIAVFVAYYVLGIRRHMGMSTLLRHTET
GFASIANILLIIGAGGAFNSILKTSGLADTLALMLSNLHMHPILLAWLVALILHAAVGSA
TVAMMGATAIVAPMLALYPDVSPEIVTIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
KYYTTATFIASVLALGMTFLLSYII