Protein Info for IAI46_01410 in Serratia liquefaciens MT49

Annotation: glutamate/aspartate:proton symporter GltP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 7 to 8 (2 residues), see Phobius details transmembrane" amino acids 9 to 26 (18 residues), see Phobius details amino acids 47 to 72 (26 residues), see Phobius details amino acids 84 to 106 (23 residues), see Phobius details amino acids 160 to 177 (18 residues), see Phobius details amino acids 206 to 228 (23 residues), see Phobius details amino acids 234 to 256 (23 residues), see Phobius details amino acids 319 to 349 (31 residues), see Phobius details amino acids 356 to 383 (28 residues), see Phobius details amino acids 391 to 411 (21 residues), see Phobius details PF00375: SDF" amino acids 8 to 411 (404 residues), 411.5 bits, see alignment E=1.9e-127

Best Hits

Swiss-Prot: 79% identical to GLTP_ECOLI: Proton/glutamate-aspartate symporter (gltP) from Escherichia coli (strain K12)

KEGG orthology group: K11102, proton glutamate symport protein (inferred from 95% identity to srs:SerAS12_0260)

MetaCyc: 79% identical to glutamate/aspartate : H+ symporter GltP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-122A; TRANS-RXN-162

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>IAI46_01410 glutamate/aspartate:proton symporter GltP (Serratia liquefaciens MT49)
MKSVKISLAWQILIALVLGIIVGAVLHNQTESREWLVSNILSPAGDIFIRLIKMIVVPIV
ISTLVVGIAGVGDAKKLGRLGLKTIIYFEVITTVAIVVGLTLANVFQPGHGIDMSTLTAV
DISQYEKTTEQVQSGSHSLVATVLSLIPSNIFASMAKGDMLPIIFFSVLFGLGLSSLPKE
TKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLWPLAKLVVLVYFA
IAFFALVVLGAVARICNLRIWTLIRILKDELILAFSTASSETVLPRIIEKMEAYGAPKAI
TSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIELSLGQEIVLVVTLMLTSKGIAGVPGV
SFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVVAKWEHQFDSKKA
RAYEQAFLSSKVKQVNES