Protein Info for HUW76_09330 in Fusobacterium nucleatum SB010

Annotation: sigma-70 family RNA polymerase sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 PF07638: Sigma70_ECF" amino acids 1 to 194 (194 residues), 27.9 bits, see alignment E=4.1e-10 PF12645: HTH_16" amino acids 6 to 62 (57 residues), 25.7 bits, see alignment E=1.9e-09 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 18 to 191 (174 residues), 79 bits, see alignment E=1.6e-26 PF04542: Sigma70_r2" amino acids 24 to 89 (66 residues), 53.1 bits, see alignment E=4.5e-18

Best Hits

KEGG orthology group: K03091, RNA polymerase sporulation-specific sigma factor (inferred from 97% identity to fnu:FN1518)

Predicted SEED Role

"RNA polymerase sigma-70 factor" in subsystem Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (204 amino acids)

>HUW76_09330 sigma-70 family RNA polymerase sigma factor (Fusobacterium nucleatum SB010)
MEDINAILKKAQSGDSEAINLILKEYSKLLSFNAQKYYLVGAEKEDLVQEGILGLLKAIK
FYDETKSSFSSFAFLCIRREMISAIRKANTQKNMVLNEALKTNAILEDSANFDDEEHNIN
NYKSSESNPEEAYLLKEEIEEFKKFSENNFSKFEKEVLTYLIRGYSYREIAKILSKNIKS
IDNTIQRIRKKSEEWIKEEENIKR