Protein Info for HUW76_01030 in Fusobacterium nucleatum SB010

Annotation: DUF448 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 176 PF04296: YlxR" amino acids 9 to 64 (56 residues), 46.6 bits, see alignment E=2.7e-16 PF01248: Ribosomal_L7Ae" amino acids 92 to 165 (74 residues), 31.7 bits, see alignment E=1e-11

Best Hits

KEGG orthology group: None (inferred from 93% identity to fnu:FN2021)

Predicted SEED Role

"COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination / ribosomal protein L7Ae family protein" in subsystem NusA-TFII Cluster or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (176 amino acids)

>HUW76_01030 DUF448 domain-containing protein (Fusobacterium nucleatum SB010)
MSNTHIPERTCIICRTKKEKSKLFRLAKLKETFYEFDKEQKKQSRAVYVCKSLNCLGKLA
KHNKVKLDSQDLMSMLNIINKANKNYINILNSMKNSGELVFGINLLFENIEHVHFIVMAQ
DISKKNEEKIIRRINELKIPYVVVGSMQELGKVFNKEEITVIGIKDKKMARGLIEE