Protein Info for HMPREF1181_RS15585 in Bacteroides stercoris CC31F

Annotation: HlyD family efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details PF13437: HlyD_3" amino acids 234 to 329 (96 residues), 41.1 bits, see alignment E=2.6e-14

Best Hits

KEGG orthology group: K02005, HlyD family secretion protein (inferred from 91% identity to bhl:Bache_2076)

Predicted SEED Role

"ABC transporter permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (415 amino acids)

>HMPREF1181_RS15585 HlyD family efflux transporter periplasmic adaptor subunit (Bacteroides stercoris CC31F)
MDREIPKEVRNKERNKKIIRYGGMGAAGIVVISVLISLMRTGVKEKDIVFSQVSTGTIEV
SVSASGKVVPAFEEIINSPINTRILEVYKKGGDSVDIGTPILKLDLQSAETDYKQKLDEE
QMRSYKLKQLKLENMTKLNDLEMKIKVSAMQLNRKKVELRNEQYLDSLGSGTTDKVRQAE
LSYNVAELEYEQLKQQYANEKEVLDAEYQVQELDFSIFRKTLAETKRTLDDAQVRSPRKA
ILTYINNQIGAQVAEGSQIAVISDLSHFKVEGEIADTYGDRIAAGGKAIVKIGSEKLEGT
VSSVTPLSKNGVISFTVQLNEDNNRRLRSGLKTDVYVMNAVKEDVMRIANASYYVGRGEY
ELFVRNSDKEIVKRKVQLGDSNFEFVEVIGGLQPGDEVVVSDMSQYKNKNKLKLK