Protein Info for HMPREF1181_RS10110 in Bacteroides stercoris CC31F

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1063 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 37 to 1063 (1027 residues), 941.7 bits, see alignment E=6.5e-287 PF13620: CarboxypepD_reg" amino acids 37 to 105 (69 residues), 32.5 bits, see alignment 1.4e-11 PF13715: CarbopepD_reg_2" amino acids 38 to 117 (80 residues), 64.5 bits, see alignment 1.1e-21 PF07715: Plug" amino acids 125 to 227 (103 residues), 72.7 bits, see alignment E=5.1e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 203 to 233 (31 residues), 52.5 bits, see alignment (E = 3.3e-18)

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1063 amino acids)

>HMPREF1181_RS10110 TonB-dependent receptor (Bacteroides stercoris CC31F)
MKKETHAMKSTRWMKAVALSFFALLLCSVNGYAQNMTVTGRVSDAMGTLPGVSVSVKGTT
SGTVTDADGKYSLNADRNATLVFSFVGMKFQEVAVNGRKVINVTMVDDAELLDEVVVVGY
GTQKKSSLTSAVSVVKGEELLKAPATNVSQLLGGRLPGISSLQESGEPGLDQASLKIRGS
VYSVSYVVDGFPVNSINDIDPNDIESVSVLKDGASAAIYGLAGAGGVIIITTKRGEVGKT
KVTYDASYGVSMNANFPKFMNGPQYAHYYNMAQMMDQLASGAIKDRNEYVPYYTKENIEA
MTNGDSTDGWDNVNYIDKVFGTGTNQKHSITVQGGNEKMRYFTSLGYMGQNGNIDNFDYR
RYNLRANIESEFAKHFNFKLGVSGVVGRRSTPAFNSGGGDNGNEEVGFLSIARQTIQMHP
YLPERYNGMYTAAIQKNTSLPNSPLAAIYESGYKKTRSLEGNVNLELTYNVPWVKGVALK
VNGSYNYSTSHNKNLNTLYSVMGYNNGTWSKYEDPRGTSDGTALGEGQTTYEQMVGQASI
NYTSNFGLHNVEALALVEARDNKGCGLSAYAKNLPFIQLPELGFGVPTKDPIGGWSIASR
TAGYVFRLKYDYNSKYMAEFTGRYDGSYKFYGMGKRWGFFPSASLGWRISKEKFMEGLDF
INDLKVRTSIGLLGNDAVSEYAFLSTYSQWKSGVIYPLGASAVKSPGIYTSGIPNPNLTW
EKTLSWNTGFDATLWNGLLSIELDAFYNYTYDVLTGMGGGKPSSMGGYYPTYGNHNALDS
KGIDILLSHRSKFQLAGSPLQYNISGNLTYSKTRWLKYLDDPNIMEWQKMVGTTYGTIYG
WKADGLFRSEEEIDNSAWYGSRPCVGDIKYVDMNGDGKIDSQDRGAFGRSNRPQLTFGLN
IGASWKGFDFNAQFTGGALFDVSLTGTYYNGYDDNTIWTQTFKENANSPLFLVENAYSID
NPNGSFPRITLGSTGHGGDNGLSSSFWWRDGKYIRLKSAQIGYTFPRTWMSKLNIQDLRI
FVEGSNLFTIDGLPEGIDPESPGVNNGYYPQQRTVMGGLTLTF