Protein Info for HMPREF1181_RS03475 in Bacteroides stercoris CC31F

Annotation: glycoside hydrolase family 88 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 842 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF03629: SASA" amino acids 105 to 359 (255 residues), 59.8 bits, see alignment E=3.3e-20 PF07470: Glyco_hydro_88" amino acids 482 to 841 (360 residues), 374.2 bits, see alignment E=6.3e-116

Best Hits

Predicted SEED Role

"Rhamnogalacturonides degradation protein RhiN" in subsystem D-Galacturonate and D-Glucuronate Utilization or L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (842 amino acids)

>HMPREF1181_RS03475 glycoside hydrolase family 88 protein (Bacteroides stercoris CC31F)
MKKLLGLISFLLVLAGSVSAKVVLPAIFSDNMVLQQNAQVNLWGKATPGERVSVKASWTD
KTVTTKAAADGKWAVKLKTPAAAKGQSVTVSGENTITINNVLVGEVWLCTGQSNMEYPVC
KHPDKKWMTGMITEAEEMKDADYPELRLFRVEHQLAPDGEMDDCQGRWLVCTPKNLYDFS
AVGFVFGRRLHKELNVPVGMIQSTWGGTHAESWTKMSVMKNNPLYADVLEDFALKNVKQE
KGYCKVPATLWNGMIHPILGYTVKGNIWYQGESNAIRHEKYQQVFTNMINSWRKEWKQPD
MPFYFMQIAPHKGQPAGIREAQLKTWQSGLKNVGMAVVTDAADSTDIHPRNKRVAGERMA
LWALAKQYGKDVAYSGPLFKTMKVSGNKAILSFEYAEDGLMTPENAPVKGFLVAGADRRF
YPAVAVIKGSRLEVFAPQVAEPVAVRYGFCNFFRVNLYNKSGLPAVPFRTDTWEQGSYAR
WFADSEMMRFPQAYRLDHGKRLFFGYAQGVGCCAMLQMWKATGERRYYDYVKQWADSLIN
EKGEIHLYDKSTYNLDFINSGKVLFDLYRETGDQRYKAAMDILIKQLKNQPRTLEGGFWH
KLIYQHQMWLDGLYMASPFMAQYGAEFNKPEWIDEAVKQFRLCHKHTYDAKTGLYHHAWD
ESKSQRWANPETGHSPNFWGRSIGWWFMALVDALDYIPENHPGRADMIGYIRGLAETLPK
YQDKAGLWYQVIDQPKRKGNFPEASVTTQCMYAYAKAVNKGYIYAGYRAVAEKALRGLKD
KLLVEKQDGTLTLTRCCQVGGLGGHPYRDGSFEYYIGEKMRDNDAKATGPFIMGCLELEK
IK