Protein Info for HMPREF1181_RS02225 in Bacteroides stercoris CC31F

Annotation: serine hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00144: Beta-lactamase" amino acids 57 to 306 (250 residues), 112.5 bits, see alignment E=1.2e-36

Best Hits

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (497 amino acids)

>HMPREF1181_RS02225 serine hydrolase (Bacteroides stercoris CC31F)
MKINLVLLTLCMLVHTSLLAQTNELQRSIPEAEGVPSEAVITLFDSLTALPHTDIHSVIV
LRHGKVIGEIYPTPFAPEYRHTMYSCSKTFVGAAVGLAIADNRLRLTDRVVSFFPEQLPD
SVSENLSNITVRHLLTMTSGITPDWNMRNVCTNWLSTFLAKPVKTPGVQFEYDSISTYVL
SAIIQKVTGMTLLDYLKLKLFNPMNIKEVAWEISPEGIHTGGWGLHIQSESLAKFGLLLL
NQGKWKGKQLLSSSWIKQMTSKQMEAGDEDYGYQMWLCDYPGAVRADGALGQYVLIMPKE
DMVVVITECTLINGRNQRRLVWNKLLSAIKNQALIPGKAYARLKKKQISYTLPTVQGKKQ
SPLATAYANRTITLETNRYGWQHLHLLFGPKEVNLKIDDKNGTSHILPFGYKQWLTGTIN
AYPPYSITPVGSFNGLEKTFHVAGSYAWLPTDDLQLKVHYVDWISALDITFHFNGNNVTL
TVKENFSTNETILKGKF