Protein Info for HMPREF1181_RS00575 in Bacteroides stercoris CC31F

Annotation: 50S ribosomal protein L1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 TIGR01169: ribosomal protein uL1" amino acids 3 to 228 (226 residues), 319.8 bits, see alignment E=4.3e-100 PF00687: Ribosomal_L1" amino acids 31 to 219 (189 residues), 221.6 bits, see alignment E=3.9e-70

Best Hits

Swiss-Prot: 97% identical to RL1_BACTN: 50S ribosomal protein L1 (rplA) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K02863, large subunit ribosomal protein L1 (inferred from 98% identity to bhl:Bache_1046)

MetaCyc: 49% identical to 50S ribosomal subunit protein L1 (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"LSU ribosomal protein L1p (L10Ae)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>HMPREF1181_RS00575 50S ribosomal protein L1 (Bacteroides stercoris CC31F)
MSKLTKNQKLAAEKIEAGKAYSLKEAAQLVKEITFTKFDASLDIDVRLGVDPRKANQMVR
GVVSLPHGTGKVTRVLVLCTPDAEAAAKEAGADYVGLDEYIEKIKGGWTDIDVIITMPSI
MGKIGALGRVLGPRGLMPNPKSGTVTMDVAKAVKEVKQGKIDFKVDKSGIVHTSIGKVSF
SADQIRDNAKEFISTLNKLKPTAAKGTYIKSIYLSSTMSAGIKIDPKSVEEI