Protein Info for HMPREF1181_RS00510 in Bacteroides stercoris CC31F

Annotation: 50S ribosomal protein L2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 TIGR01171: ribosomal protein uL2" amino acids 3 to 274 (272 residues), 389.5 bits, see alignment E=4.2e-121 PF00181: Ribosomal_L2" amino acids 42 to 117 (76 residues), 100 bits, see alignment E=6.1e-33 PF03947: Ribosomal_L2_C" amino acids 126 to 249 (124 residues), 178.7 bits, see alignment E=4.7e-57

Best Hits

Swiss-Prot: 96% identical to RL2_BACFR: 50S ribosomal protein L2 (rplB) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: K02886, large subunit ribosomal protein L2 (inferred from 98% identity to bhl:Bache_1059)

MetaCyc: 54% identical to 50S ribosomal subunit protein L2 (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"LSU ribosomal protein L2p (L8e)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>HMPREF1181_RS00510 50S ribosomal protein L2 (Bacteroides stercoris CC31F)
MAVRKFKPTTPGQRHKIIGTFEEITARVPEKSLVFGKKSSGGRNNTGKMTMRYIGGGSKK
IIRIVDFKRNKDGVPAVVKTIEYDPNRSARIALLFYADGEKRYIIAPNGLQVGATLMSGE
TAAPEIGNALPLQNIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSREGRYCVIKLPSGE
VRQILSTCKATIGSVGNSDHGLESSGKAGRSRWLGRRPRNRGVVMNPVDHPMGGGEGRAS
GGHPRSRKGLYAKGLKTRAPKKQSSKYIIERRKK