Protein Info for HMPREF1181_RS00450 in Bacteroides stercoris CC31F

Annotation: 50S ribosomal protein L6

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 189 TIGR03654: ribosomal protein uL6" amino acids 2 to 185 (184 residues), 228.3 bits, see alignment E=2.6e-72 PF00347: Ribosomal_L6" amino acids 11 to 87 (77 residues), 58.4 bits, see alignment E=5.1e-20 amino acids 95 to 172 (78 residues), 66 bits, see alignment E=2.2e-22

Best Hits

Swiss-Prot: 96% identical to RL6_BACFR: 50S ribosomal protein L6 (rplF) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: K02933, large subunit ribosomal protein L6 (inferred from 95% identity to bth:BT_2712)

Predicted SEED Role

"LSU ribosomal protein L6p (L9e)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (189 amino acids)

>HMPREF1181_RS00450 50S ribosomal protein L6 (Bacteroides stercoris CC31F)
MSRIGKLPISIPAGVTVTLKDDVVTVKGPKGELSQYVNPAINVAIEEGHVVLTENENAML
DNPKQKHAFHGLYRSLVHNMVVGVSEGYKKELELVGVGYRASNQGNIIELNLGYTHSIFI
QLPAEIKVETKSERNKNPLILLESCDKQLLGQVCSKIRSFRKPEPYKGKGIKFVGEEIRR
KSGKSAGAK