Protein Info for HGI48_RS21630 in Dickeya dianthicola 67-19

Annotation: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 transmembrane" amino acids 242 to 272 (31 residues), see Phobius details amino acids 277 to 302 (26 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 16 to 199 (184 residues), 54.3 bits, see alignment E=2.8e-18 PF00535: Glycos_transf_2" amino acids 18 to 179 (162 residues), 117.3 bits, see alignment E=1.1e-37

Best Hits

Swiss-Prot: 81% identical to ARNC_SODGM: Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (arnC) from Sodalis glossinidius (strain morsitans)

KEGG orthology group: K10012, undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [EC: 2.7.8.30] (inferred from 97% identity to ddd:Dda3937_01079)

MetaCyc: 76% identical to undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (Escherichia coli K-12 substr. MG1655)
RXN0-3521 [EC: 2.4.2.53]

Predicted SEED Role

"Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-)" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance ) (EC 2.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-

Use Curated BLAST to search for 2.4.-.- or 2.4.2.53 or 2.7.8.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RKA9 at UniProt or InterPro

Protein Sequence (334 amino acids)

>HGI48_RS21630 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (Dickeya dianthicola 67-19)
MLHRETLHSNVEAINKVSVVIPVFNEQESLPELIRRTTAACDQMNRDYEILLVDDGSSDN
SAALLTKAAQAPGSHVVAVILNRNYGQHSAIMAGFSHVSGDLVITLDADLQNPPEEIPRL
VDTADQGYDVVGTIRENRQDSWFRKSASRMINHLIQRTTGKAMNDYGCMLRAYRRHIIDA
MMHCHERSTFIPILANTFARRTTEIMVRHSEREFGDSKYSFMKLINLMYDLVTCLTTTPL
RLLSVVGSVIALSGFTLALLLILLRLFFGAAWAADGVFTLFAVLFSFIGAQFVGMGLLGE
YIGRIYNDVRARPRYFIQRIVSHDPRFSEQDNEE