Protein Info for HGI48_RS20660 in Dickeya dianthicola 67-19

Annotation: MCP four helix bundle domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 195 to 214 (20 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 6 to 186 (181 residues), 60.9 bits, see alignment E=1.2e-20 PF00015: MCPsignal" amino acids 331 to 487 (157 residues), 185.8 bits, see alignment E=6.1e-59

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 95% identity to ddd:Dda3937_02028)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RII0 at UniProt or InterPro

Protein Sequence (560 amino acids)

>HGI48_RS20660 MCP four helix bundle domain-containing protein (Dickeya dianthicola 67-19)
MNALKKMKLGTMLSAGFALVIVIGLLVATFGRTQLAGLGDDIDHLSTTTLTNMMLIQEAK
TGFDTNSRLVRNIALSNDPERITREKALIDRQIARNTEVLKQLSERLDTPETREQLNQLT
LARPAYLQAFNKAVQLGISGQPELRDQARELILNDMQTAQNGVFKALDNMLDFQKKITMN
VVTDSMQNARSDGTVMLALALVAAVLGALTAWLITRTVKGQLGGEPVYAAAVAQRIADGN
LAFNIELRTGDNHSVLAAMNEMREKLGQIVTQVRQSSESIATGASEIAAGSTDLSQRTEE
QAASLQQTAASMEQMSQTIRQNGETVRTATTLAQSASSTAARGGEAVNNIVRTMEDISHS
SHKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSASAAKEI
KELITASVEKVETGSTLVSEAGSTIDELVKQARHVADLIGEIGVTTHEQESGISQINDAV
NQLDQVTQQNASLVEESASAADSLSDQAAKLVELMSVFNIQNAFSHQTTLLQKPGTGQKK
PTPSKLALANNASSSNWEQF