Protein Info for HGI48_RS17405 in Dickeya dianthicola 67-19

Annotation: PTS glucose transporter subunit IIA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 632 transmembrane" amino acids 113 to 139 (27 residues), see Phobius details amino acids 145 to 167 (23 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details amino acids 246 to 271 (26 residues), see Phobius details amino acids 286 to 312 (27 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 355 to 373 (19 residues), see Phobius details amino acids 383 to 402 (20 residues), see Phobius details amino acids 422 to 446 (25 residues), see Phobius details TIGR01995: PTS system, beta-glucoside-specific IIABC component" amino acids 5 to 627 (623 residues), 655.1 bits, see alignment E=1.1e-200 PF00367: PTS_EIIB" amino acids 10 to 43 (34 residues), 41.8 bits, see alignment (E = 8.9e-15) PF02378: PTS_EIIC" amino acids 111 to 390 (280 residues), 143.4 bits, see alignment E=1.3e-45 PF00358: PTS_EIIA_1" amino acids 482 to 605 (124 residues), 147 bits, see alignment E=3.5e-47 TIGR00830: PTS system, glucose subfamily, IIA component" amino acids 483 to 603 (121 residues), 131.9 bits, see alignment E=1.2e-42

Best Hits

KEGG orthology group: K02755, PTS system, beta-glucosides-specific IIA component [EC: 2.7.1.69] K02756, PTS system, beta-glucosides-specific IIB component [EC: 2.7.1.69] K02757, PTS system, beta-glucosides-specific IIC component (inferred from 95% identity to ddd:Dda3937_02589)

Predicted SEED Role

"PTS system, beta-glucoside-specific IIB component (EC 2.7.1.69) / PTS system, beta-glucoside-specific IIC component / PTS system, beta-glucoside-specific IIA component" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RHD7 at UniProt or InterPro

Protein Sequence (632 amino acids)

>HGI48_RS17405 PTS glucose transporter subunit IIA (Dickeya dianthicola 67-19)
MSVNYQETAKNIVALVGGEGNIRQVFHCITRLRFYLHEAQRIDRAQLEALDGVIGINVAG
EQFQVIIGNEVADVYRALIRQYPQLASQPAGAPQAGRPRHPVSALLEAFSSIFSPVIPAI
AGAGILKGILSLLVALHWVSNTNQTYLILSAISDGIFYFMPLVLAFSAAHQFGGNPYVAV
ALAATLLHPTLMKLFAGGGEISFLGLPVSPVSYASSVIPILLAVWLMSWVERRVDRIMPG
ALKTMFVPLLTLLIVAPIMLIAIGPLGIIVGNHLSSGIVWLVDNMGILAGLILGGTLSMI
IITGMHYVLIPIMINNISKMGFDPFKIIFYIANMGQAGAAFGVFLRARDKKTKSLALSTS
ITATMGITEPAMYGVNIRFKRPFAAALIGGACGGAFAMFFGVKTYAFALSGLPGLPALVG
PTFLYALASMAISFTTATVMTCVLGFEEHLENAAIPRAGQTVMPAAPVALSEHNEKLFHN
EKLFAPVAGRVVSLESLSDPVFAGEVFGKGIAIYPESGELLSPVNGRVESIFDTHHALTL
KSDTGAEVLIHIGIDTVKLGGRHFIRHAQPGQIVEVGEPLVSFDLPALLAEGIDPSVIVI
VTNTECYGEVYPLLNGDVHSRDALMKLTAAAV