Protein Info for HGI48_RS16035 in Dickeya dianthicola 67-19

Annotation: ATP-dependent helicase HrpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 833 TIGR01970: ATP-dependent helicase HrpB" amino acids 5 to 830 (826 residues), 1098.3 bits, see alignment E=0 PF00270: DEAD" amino acids 12 to 162 (151 residues), 40.9 bits, see alignment E=2.7e-14 PF00271: Helicase_C" amino acids 205 to 327 (123 residues), 51.2 bits, see alignment E=2e-17 PF08482: HrpB_C" amino acids 686 to 818 (133 residues), 173.2 bits, see alignment E=5.3e-55

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 93% identity to ddd:Dda3937_00507)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RGM1 at UniProt or InterPro

Protein Sequence (833 amino acids)

>HGI48_RS16035 ATP-dependent helicase HrpB (Dickeya dianthicola 67-19)
MSLPPVSAVLDEVIRALHIAPQVLLHAPTGAGKSTWLPLQLLQRSGFPGRIIMLEPRRLA
AKSVAFRLAEWLGETPGQTVGYRMRSESRVSSRTRLEVVTEGILTRMLQHDPALEGVSLV
MLDEFHERSLQADLALGLLLDVQQGLRDDLKLLIMSATLDNSRLSSLLPQSLSVSSQGRC
WPVERHYQPVGSQERLEDAAARLVYRVLQDETGSLLVFLPGVAEIKRLQTLLENAVPAEV
DICPLYGALTLAEQQKAILPAAAGRRKVVLATNIAETSLTIEGIRVVVDSGLERVALFDV
KTGLTRLTTQRISQASMVQRAGRAGRLEPGVCWHLFVREQAERAAAQSEPEILHSDLSGL
RLDLLQWGCGDVAQLCWLDMPPQPALLAADRLLMQLGMCDVQQRLTTSGRKMAELGCDPR
LAAMLHAAGQEPDALATAALLAAIIEEPPRAGSPNLSDALHRPAGHWQRRAQQLARRAGK
ASGKVNADEVNAGKVNAGKVNAGKVNDNLAAWLLSAGFADRIARRRGQDGRYQLANGSGA
SLPPEDALAASEWLLTPVLMQSPNNADARILLALPVDIDPLVRQRPELVTEQNLMHWDEE
KGTLRASLRTQIGSLTLSSRPLAKPSDEALQQAMLNWLREQGLSVLNWDEPALQLRQRLL
CARQWLPEAAWPAVDDAALLASLERWLLPSLNSVRDRRTLHQINLSDALWRLLDWSQRQR
LDSALPSHYTAPGGSRLPIRYDADLPPVLAVRLQEMFGEQRSPLLAEGRVALVLELLSPA
MRPLQITRDLAAFWQGAYREVQKEMKGRYPKHVWPDDPANTAPTRRTRKYQNS