Protein Info for HGI48_RS12795 in Dickeya dianthicola 67-19

Annotation: PTS beta-glucoside transporter subunit IIABC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 631 transmembrane" amino acids 106 to 134 (29 residues), see Phobius details amino acids 144 to 166 (23 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 205 to 228 (24 residues), see Phobius details amino acids 248 to 272 (25 residues), see Phobius details amino acids 285 to 312 (28 residues), see Phobius details amino acids 328 to 348 (21 residues), see Phobius details amino acids 359 to 379 (21 residues), see Phobius details amino acids 386 to 405 (20 residues), see Phobius details amino acids 431 to 452 (22 residues), see Phobius details TIGR01995: PTS system, beta-glucoside-specific IIABC component" amino acids 3 to 627 (625 residues), 707.8 bits, see alignment E=1.3e-216 PF00367: PTS_EIIB" amino acids 9 to 41 (33 residues), 46.7 bits, see alignment (E = 2.6e-16) PF02378: PTS_EIIC" amino acids 109 to 393 (285 residues), 109.3 bits, see alignment E=3.1e-35 PF00358: PTS_EIIA_1" amino acids 484 to 609 (126 residues), 166.6 bits, see alignment E=3.1e-53 TIGR00830: PTS system, glucose subfamily, IIA component" amino acids 485 to 605 (121 residues), 150.9 bits, see alignment E=1.6e-48

Best Hits

Swiss-Prot: 93% identical to PTV3B_DICCH: PTS system beta-glucoside-specific EIIBCA component (arbF) from Dickeya chrysanthemi

KEGG orthology group: K02755, PTS system, beta-glucosides-specific IIA component [EC: 2.7.1.69] K02756, PTS system, beta-glucosides-specific IIB component [EC: 2.7.1.69] K02757, PTS system, beta-glucosides-specific IIC component (inferred from 93% identity to ddd:Dda3937_03833)

Predicted SEED Role

"PTS system, beta-glucoside-specific IIB component (EC 2.7.1.69) / PTS system, beta-glucoside-specific IIC component / PTS system, beta-glucoside-specific IIA component" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9REH8 at UniProt or InterPro

Protein Sequence (631 amino acids)

>HGI48_RS12795 PTS beta-glucoside transporter subunit IIABC (Dickeya dianthicola 67-19)
MNYETLASEISDGVGGQGNIISVIHCATRLRFKLRDNANANADALKNNPGIIMVVESGGQ
FQVVVGNQVADVYQALLALDGMARFSEPAASEEQKQDSLFARFIDIISSIFTPFVGVMAA
TGILKGFLALGVATHVMSDSSGTYKLLFAASDALFYFFPIVLGYTAGKKFGGNPFTTLVI
GATLVHPSMIAAFNAMQAPDHPTLHFLGIPITFINYSSSVIPILFASWVSCKLEKPLNRW
LHANIRNFFTPLLCLVISVPLTFLLIGPSATWLSQMLSGGYQWLYGLNSLLAGAVMGALW
QVCVIFGLHWGFVPLMLNNLSVMGHDTLLPLLTPAVLGQAGATLGVLLRTRDMKRKGIAG
SAFSAAIFGISEPAVYGVTLPLRRPFIFGCIGGALGAAVMGYFHTTSYSFGFPSIFTFTQ
IIPPTGVDSSVWAAVIGTLAAFVVAALTSWSFGVPKEETQPAAAGSPTVATQTQGSAGAV
RDETLFSPLAGEVLPLEQVADRTFASGVMGKGIAIRPSQGRLYAPADGTVASLFKTHHAI
GLASRGGAEVLIHVGIDTVRLDGRYFTPHVRVGDVVRQGDLLLEFDGPAIEAAGYDLTTP
MVITNSEDYRGVEPVASGKVDANAPLTQLVC