Protein Info for HGI48_RS08665 in Dickeya dianthicola 67-19
Annotation: glycoside hydrolase family 3 protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 92% identical to BGLX_DICCH: Periplasmic beta-glucosidase/beta-xylosidase (bgxA) from Dickeya chrysanthemi
KEGG orthology group: K05349, beta-glucosidase [EC: 3.2.1.21] (inferred from 94% identity to ddd:Dda3937_03745)Predicted SEED Role
"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)
MetaCyc Pathways
- peptidoglycan recycling I (13/14 steps found)
- cellulose degradation II (fungi) (2/3 steps found)
- neolinustatin bioactivation (2/3 steps found)
- linamarin degradation (1/2 steps found)
- lotaustralin degradation (1/2 steps found)
- linustatin bioactivation (2/4 steps found)
- peptidoglycan recycling II (6/10 steps found)
- coumarin biosynthesis (via 2-coumarate) (2/5 steps found)
- chitin degradation II (Vibrio) (2/6 steps found)
- chitin degradation III (Serratia) (2/7 steps found)
- α-tomatine degradation (1/6 steps found)
- firefly bioluminescence (3/14 steps found)
KEGG Metabolic Maps
- Aminosugars metabolism
- Cyanoamino acid metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo series
- Nucleotide sugars metabolism
- Other glycan degradation
- Phenylpropanoid biosynthesis
- Starch and sucrose metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.21, 3.2.1.52
Use Curated BLAST to search for 3.2.1.21 or 3.2.1.52
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A7L9RCF2 at UniProt or InterPro
Protein Sequence (658 amino acids)
>HGI48_RS08665 glycoside hydrolase family 3 protein (Dickeya dianthicola 67-19) MTSRYAPHAAVVLPWVATLPLLFSPLAEALQQATLDTREAPLITVGGLKFKDLNRDGKLN PYEDWRLPPAQRAADLVSRMTLAEKAGVMMHGSAPTAGSVTGAGNQYDLKAANVMIAERH VNSVITRLSGDNPAQMAEENNKLQQLAENTRLGIPATISTDPRNSFQSLVGVSVSVGKFS KWPETLGLAAIGDEERVRRFADIVRQEYRAVGITEALSPQADLSTEPRWPRIDGTFGEDP DLTKKMVRGYVTGMQNGKNGLNGQSVISVVKHWVGYGAAQDGWDSHNAYGKYARFRQNNL QWHIDPFTGAFEARAAGIMPTYSILRNARWHGKPIEPVGAGFNRFLLTDLLRGQYGFDGV ILSDWLITNDCKGDCLTGVKPGEKPLPRGMPWGVENLTPAERFIKAVNAGVDQFGGVTDS GLLVKAVQDGLLSEARLDTSVNRILKQKFQTGLFERPYVNAAQANDIVGRADWQQLADDS QARALVLLQNNNLLPLRKGSRVWLHGIEANAAQAAGFIVVDAPEQAGVALIRTHTPYEQP HKNFFFGSRHHEGSLAFRADNPDYQAIVRASARVPTLVTVYMERPAILTNVVGKTQALVA NFGVSDSVLLNRLISGAAYTAKLPFELPSSMQAVLKQQPDLPYDSDKPLFPFGYGLPH