Protein Info for HGI48_RS08345 in Dickeya dianthicola 67-19

Annotation: restriction endonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF05066: HARE-HTH" amino acids 1 to 40 (40 residues), 28.3 bits, see alignment 2.8e-10 PF04471: Mrr_cat" amino acids 127 to 247 (121 residues), 109.2 bits, see alignment E=2e-35 PF13156: Mrr_cat_2" amino acids 149 to 246 (98 residues), 29.8 bits, see alignment E=8.1e-11

Best Hits

KEGG orthology group: K07448, restriction system protein (inferred from 91% identity to ecy:ECSE_4574)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RCF5 at UniProt or InterPro

Protein Sequence (273 amino acids)

>HGI48_RS08345 restriction endonuclease (Dickeya dianthicola 67-19)
MTIIEAIINVLKEHGKPLSHKDIYDCIINKKYYSFGAKDPVSVVRGEIRKHCYGINFPSA
SPRKIFIEVKSVGQSKPLYDLWQGQVSHFHLLKVEKATKDQLPEEIIHGKYLEHISTIKN
QLLDAINSSDPAFFERFVVTLLLKMGYGWHESESGKVIGGAGDEGIDGVINEDKLGLEKI
YIQAKRYNNKKVPPSEIREFIGSMNQKGAHKGVFFSSSSFTEQAMNSAEKAQGMTITLID
GVQLCEYLVQNGMGVAKVSTYELYEIDRNFFDL