Protein Info for HGI48_RS07735 in Dickeya dianthicola 67-19

Annotation: ABC transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 53 to 77 (25 residues), see Phobius details amino acids 83 to 108 (26 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 146 to 170 (25 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 47 to 214 (168 residues), 73.7 bits, see alignment E=8.1e-25

Best Hits

Swiss-Prot: 51% identical to METI_VIBCH: Probable D-methionine transport system permease protein MetI (metI) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02072, D-methionine transport system permease protein (inferred from 97% identity to ddd:Dda3937_03008)

MetaCyc: 44% identical to L-methionine/D-methionine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
RXN0-4522 [EC: 7.4.2.11]; 7.4.2.11 [EC: 7.4.2.11]; TRANS-RXN-383 [EC: 7.4.2.11]; TRANS-RXN0-510 [EC: 7.4.2.11]; TRANS-RXN0-511 [EC: 7.4.2.11]

Predicted SEED Role

"Methionine ABC transporter permease protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RJB2 at UniProt or InterPro

Protein Sequence (219 amino acids)

>HGI48_RS07735 ABC transporter permease subunit (Dickeya dianthicola 67-19)
MSWDDFFPIMLNATLETLYMVGLAALFTVLVGLPTGVLLFISRQSGIMPLPRVNAVLGGV
INLGRSLPFVVLLIALIPFTRWVVGTTLGSTAAVVPIAVGAFPFFARIVENALDEVDSGR
VEAIVSMGGTVWHVITKALLPEALPSILAGITLTVVMLIGFSSMAGVIGGGGLGDLAIRY
GYQRFNQQVMAGTVIVLVLLVQLVQSLGDRLVRSLAYRR