Protein Info for HGI48_RS02855 in Dickeya dianthicola 67-19

Annotation: hexose-6-phosphate:phosphate antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 58 to 85 (28 residues), see Phobius details amino acids 97 to 117 (21 residues), see Phobius details amino acids 121 to 142 (22 residues), see Phobius details amino acids 161 to 185 (25 residues), see Phobius details amino acids 192 to 212 (21 residues), see Phobius details amino acids 260 to 278 (19 residues), see Phobius details amino acids 298 to 318 (21 residues), see Phobius details amino acids 327 to 345 (19 residues), see Phobius details amino acids 353 to 379 (27 residues), see Phobius details amino acids 392 to 411 (20 residues), see Phobius details amino acids 423 to 446 (24 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 397 (363 residues), 120.9 bits, see alignment E=3.1e-39 TIGR00881: phosphoglycerate transporter family protein" amino acids 36 to 426 (391 residues), 466.6 bits, see alignment E=3.1e-144

Best Hits

Swiss-Prot: 92% identical to UHPT_SALTY: Hexose-6-phosphate:phosphate antiporter (uhpT) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K07784, MFS transporter, OPA family, hexose phosphate transport protein UhpT (inferred from 96% identity to ddc:Dd586_0565)

MetaCyc: 91% identical to hexose-6-phosphate:phosphate antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-33; TRANS-RXN0-501; TRANS-RXN0-502; TRANS-RXN0-534

Predicted SEED Role

"Hexose phosphate transport protein UhpT" in subsystem Hexose Phosphate Uptake System

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9R9N0 at UniProt or InterPro

Protein Sequence (463 amino acids)

>HGI48_RS02855 hexose-6-phosphate:phosphate antiporter (Dickeya dianthicola 67-19)
MLNFLTQVRQPTLSLPLDARRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMIGTY
GLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGTGS
VSLFLMIACYALSGFFQSTGGSCSYSTITKWTPRRKRGTYLGLWNISHNLGGAGAAGVAL
FGANYLFDGHVVGMFIFPSIIALIVGFIGLRFGSDSPEAYGLGKAEELFDEAISEEDKEA
EDGAMTKWQIFVEYVLKNKVIWLLCFSNIFLYVVRIGIDQWSTVYAYQELKLPKSVAIQG
FTLFEAGALVGTLLWGWLSDLANGRRGLVACVALALIIVTLGVYQHAGNQYVYLSSLFAL
GFLVFGPQLLIGVAAVGFVPKKAISAADGIKGTFAYLIGDSFAKLGLGMIADGTPIFGLT
GWAGTFAALDAAAIGCICLMAMVAVMEERKIRREKRLRQMQTA