Protein Info for HGI48_RS00285 in Dickeya dianthicola 67-19

Annotation: superoxide dismutase [Mn]

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00081: Sod_Fe_N
  • amino acids 2 to 89 (88 residues), 112.9 bits, E=8.3e-37
• PF02777: Sod_Fe_C
  • amino acids 96 to 202 (107 residues), 143.1 bits, E=2.6e-46

Best Hits

Swiss-Prot: 83% identical to SODM_YEREN: Superoxide dismutase [Mn] (sodA) from Yersinia enterocolitica

KEGG orthology group: K04564, superoxide dismutase, Fe-Mn family [EC: 1.15.1.1] (inferred from 96% identity to ddd:Dda3937_00990)

MetaCyc: 84% identical to superoxide dismutase (Mn) (Escherichia coli K-12 substr. MG1655)
Superoxide dismutase. [EC: 1.15.1.1]

Predicted SEED Role

"Manganese superoxide dismutase (EC 1.15.1.1)" in subsystem Nitric oxide synthase or Oxidative stress (EC 1.15.1.1)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethene biosynthesis III (microbes) (6/7 steps found)
• superoxide radicals degradation (2/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.15.1.1

Use Curated BLAST to search for 1.15.1.1

Sequence Analysis Tools

See A0A7L9R8C7 at UniProt or InterPro

Protein Sequence (208 amino acids)

>HGI48_RS00285 superoxide dismutase [Mn] (Dickeya dianthicola 67-19)
MSYSLPSLPYDYDALEPHFDARTMEIHHSKHHQAYVNNANAALESLPEFAGLSAEELITK
LDQLPADKKGPLRNNAGGHANHSLFWKGLKLGTTLEGELKAAIERDFGSVDAFKEKFEQA
AATRFGSGWAWLVLKDDGKLAVVSTANQDSPLMGEAISGASGYPIIALDVWEHAYYLQYQ
NRRPDYIKAFWYVVNYDEAAKRFAEAKK