Protein Info for HER17_RS18170 in Pectobacterium carotovorum WPP14

Annotation: LLM class flavin-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 54 to 69 (16 residues), see Phobius details TIGR03558: luciferase family oxidoreductase, group 1" amino acids 10 to 329 (320 residues), 450.3 bits, see alignment E=2e-139 PF00296: Bac_luciferase" amino acids 16 to 246 (231 residues), 129.9 bits, see alignment E=6.8e-42

Best Hits

Swiss-Prot: 71% identical to YHBW_ECOLI: Luciferase-like monooxygenase (yhbW) from Escherichia coli (strain K12)

KEGG orthology group: K00494, alkanal monooxygenase (FMN-linked) [EC: 1.14.14.3] (inferred from 96% identity to pct:PC1_0592)

Predicted SEED Role

"FIG00904616: hypothetical protein"

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.14.14.3

Use Curated BLAST to search for 1.14.14.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>HER17_RS18170 LLM class flavin-dependent oxidoreductase (Pectobacterium carotovorum WPP14)
MSTPSQSTVFSVLDLAPIPQGATARDAFHRSLDLAQQTEKWGYHRYWLAEHHSMTGIASA
ATSVLLGYLASGTQRIRLGSGGVMLPNHSPLVIAEQFGTLESLYPGRIDLGLGRAPGTDQ
RTMMALRRHLNADIEDFPRDVQELQRYFADAQPGQPVQAVPGQGLHVPIWLLGSSLYSAQ
LAARLGLPFAFAAHFAPDMLLEAFRLYRENFVPSTTHAKPYAMVCVNVVAADSDRDARFL
FTSMQQQFINLRRGTPGPLPAPVENIDTVGSPAEQFGTDQALRLSIVGDSVKVRHGLQSL
LRETQADEVMINGQIFDHQARLRSFEIAMDVRQTL