Protein Info for HER17_RS17255 in Pectobacterium carotovorum WPP14

Annotation: TonB family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 transmembrane" amino acids 46 to 65 (20 residues), see Phobius details PF03544: TonB_C" amino acids 243 to 312 (70 residues), 46.4 bits, see alignment E=2.4e-16 TIGR01352: TonB family C-terminal domain" amino acids 244 to 314 (71 residues), 47.5 bits, see alignment E=8.7e-17

Best Hits

KEGG orthology group: None (inferred from 83% identity to pct:PC1_0759)

Predicted SEED Role

"Ferric siderophore transport system, periplasmic binding protein TonB" in subsystem Campylobacter Iron Metabolism or Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>HER17_RS17255 TonB family protein (Pectobacterium carotovorum WPP14)
MSRENLQGALLGANRTGRSVLLGSRPLAHSYPTAALTSDAPNWRSLAFFVLSCVAHAALA
LFFLLHSSPKESIEDMAGNAGGSMQVTMMAAAMAQQADSSLPTEESSDPPVVATQTVSLE
QPISPPLPEHPNPVIKQPVIERKPVTPVAEKRPPVREKKQPEKKPESKPKEQQQQATQQQ
TEKKSESPVATNQTGDAPSLMQASAGMPGSAATAKAGESDSGQAARGAGKSNSQNFRALH
RRVNYPSRAKALGVEGKVRVKFDITGSGTVTNVQILSETPDGVFGDDVMKDMARWRYRTE
APVENQVVSIVFKLNGHIRVDDQQ