Protein Info for HER17_RS15010 in Pectobacterium carotovorum WPP14

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF13531: SBP_bac_11" amino acids 34 to 278 (245 residues), 93.8 bits, see alignment E=2.7e-30 PF01547: SBP_bac_1" amino acids 39 to 275 (237 residues), 77.4 bits, see alignment E=4.2e-25 PF13416: SBP_bac_8" amino acids 44 to 291 (248 residues), 89.8 bits, see alignment E=5.6e-29 PF13343: SBP_bac_6" amino acids 77 to 293 (217 residues), 108 bits, see alignment E=1.1e-34

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 98% identity to eca:ECA1346)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>HER17_RS15010 ABC transporter substrate-binding protein (Pectobacterium carotovorum WPP14)
MKNTLFTMNQRGIIMGIALSLAAVAGSAQALTLYTAGPGALAKKLAAGYEKQTGVKVDVF
QATTGKVMARLEAEQANPRADILISASWDTATDLQQRGWLLEFDSPNAATVPAQFKTPFY
VAQGISALGIVWNSKSGTPEPKDWNDLTKPEFKDKVTTPDPALSGASLDLLIGLQNAEKD
KAWEMFDRLKANGMIIAGPNAQALTPVLQGAKAAVFGAVDYVSYGSMESGESIKVIFPSS
GTVIAPRPMMILKSSKNQQQAKDFINYMLSPEGQKAVAEAWLMPARQDIDAKRPLFKSLT
LLPEGDSASASRAAVLDRFAALFGQR