Protein Info for HER17_RS14370 in Pectobacterium carotovorum WPP14

Annotation: iron ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 565 transmembrane" amino acids 26 to 49 (24 residues), see Phobius details amino acids 69 to 94 (26 residues), see Phobius details amino acids 103 to 124 (22 residues), see Phobius details amino acids 156 to 174 (19 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 256 to 278 (23 residues), see Phobius details amino acids 303 to 327 (25 residues), see Phobius details amino acids 350 to 372 (23 residues), see Phobius details amino acids 391 to 411 (21 residues), see Phobius details amino acids 429 to 455 (27 residues), see Phobius details amino acids 477 to 499 (23 residues), see Phobius details amino acids 536 to 554 (19 residues), see Phobius details PF00528: BPD_transp_1" amino acids 85 to 273 (189 residues), 55.2 bits, see alignment E=4e-19 amino acids 380 to 555 (176 residues), 37 bits, see alignment E=1.5e-13

Best Hits

KEGG orthology group: K02011, iron(III) transport system permease protein (inferred from 97% identity to eca:ECA1469)

Predicted SEED Role

"Ferric iron ABC transporter, permease protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (565 amino acids)

>HER17_RS14370 iron ABC transporter permease (Pectobacterium carotovorum WPP14)
MDSINKTGSSTLRGAFGRPRLFFSPLRIAAVVIALGVLAPLVSLLWLAAGAGVGHWDHLM
RYVLPDAALNTLILLVGVGALVMVIGAGCAWLVTAFDFPGRQFVSWALLLPLAMPTYIVA
FAWLDLLHPIGPIQEAIRSVLGYDSPRQFRLPDLRSMTGAILLLGLVLYPYVYLTMRAMF
ISQPAHLLEAARTLGLSATGTFLHVALPMARPALAVGTSLALLETLNDIGASEFLGVNTL
TVTVYTTWVTRSDLPAAAQIACTMLTVVILLLTLEYYGRKNQRYGTSRQMRGILPAPLKG
VRAWLATGATALPILLGFIAPALFLAWESAKRLGDSVTISASLIQSLQNSLLLAVGVTLV
VTFVSLIIAWYARHSAIADRSPERRRTLLRIASLGYAVPGTVLAIGMLTPGMATDNFLAE
LIGYKGLPLLSAGILLVICCAIRFMAIGIGALDAGLTRIPPVMEQASRLLGESEFVTFFR
VHLPLLRPALVTSALLVFADAMKELPATLLLRPVNFETLATVLYAEAARGTYEEGAIAAL
LIVLAGTLPVVLLARSQLKTSVEKE