Protein Info for HER17_RS14230 in Pectobacterium carotovorum WPP14

Annotation: amino acid racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR00035: aspartate racemase" amino acids 2 to 227 (226 residues), 179.9 bits, see alignment E=3e-57 PF01177: Asp_Glu_race" amino acids 8 to 221 (214 residues), 160.3 bits, see alignment E=3.1e-51

Best Hits

Swiss-Prot: 38% identical to RACD_PYRHO: Aspartate racemase (PH0670) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

KEGG orthology group: K01779, aspartate racemase [EC: 5.1.1.13] (inferred from 95% identity to eca:ECA1500)

Predicted SEED Role

"Aspartate racemase (EC 5.1.1.13)" in subsystem Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 5.1.1.13)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.1.1.13

Use Curated BLAST to search for 5.1.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (238 amino acids)

>HER17_RS14230 amino acid racemase (Pectobacterium carotovorum WPP14)
MNSLVGILGGMGPGATVDAMQKLIKNTPAYRDQDHIPMIAVSIPDIPDRTQCILQHSASP
LDKMLQYMKILENAGAECIIIPCNTAHYWFNDLKQQCRAEMISIIDVTCQAIKHANTTRV
GLLATTATVKARIYQDNLITDNIDCYTPDDADQHQVMESIYAYKSGDIAGAYSLLSPVKD
RLLQAGVEKIILGCTELPLILEQEVRTSPQHYVDATEELIKKTVEWYFTHNTRNNIAA