Protein Info for HER17_RS13830 in Pectobacterium carotovorum WPP14

Annotation: multidrug effflux MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 49 to 68 (20 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 207 to 233 (27 residues), see Phobius details amino acids 252 to 270 (19 residues), see Phobius details amino acids 282 to 300 (19 residues), see Phobius details amino acids 306 to 334 (29 residues), see Phobius details amino acids 346 to 366 (21 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 13 to 389 (377 residues), 282 bits, see alignment E=5.2e-88 PF07690: MFS_1" amino acids 22 to 359 (338 residues), 166.3 bits, see alignment E=9.5e-53 PF00083: Sugar_tr" amino acids 51 to 189 (139 residues), 37.5 bits, see alignment E=1.4e-13

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 95% identity to pct:PC1_1458)

Predicted SEED Role

"FIG00905076: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>HER17_RS13830 multidrug effflux MFS transporter (Pectobacterium carotovorum WPP14)
MTQIQTRPEKTSGLFFIAILSALMAFTSLSTDIYLPAMPIMAKDLQGNAELTITGFLIGF
CIAQLIWGPLSDHLGRRIPLFIGMVLFIIGSVGCALSTDMPQIVFWRVFQALGACTGPML
ARAMIRDLFSRTRAAQMLSTLMIVMAIAPIAGPLLGGQLIKVTSWHAIFWLLAVIGVVML
ISLRWLPETLPADRRVKASLPSAFRNYYALLTNANFMCFTLCLTFYYVAAYAFITGSAFV
YITYFGIDPQHYGWLFALNIVGVMGMSVVNRRLVQRYPLEKLLKFAVLIAAAASFILAIG
TKLHIGGIILIVVSVFVFFSMNGIIAATSTAAALDAVPNMAGSASALIGSLQYGSGIISS
LLLALLSDGTPWTMAWIIALFTAASAVIALTTPVTKTAS