Protein Info for HER17_RS13205 in Pectobacterium carotovorum WPP14

Annotation: TolC family outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 19 to 441 (423 residues), 417.8 bits, see alignment E=2.5e-129 PF02321: OEP" amino acids 22 to 214 (193 residues), 72.4 bits, see alignment E=2.2e-24 amino acids 240 to 426 (187 residues), 95.3 bits, see alignment E=2.1e-31

Best Hits

Swiss-Prot: 73% identical to PRTF_DICCH: Proteases secretion protein PrtF (prtF) from Dickeya chrysanthemi

KEGG orthology group: K12538, outer membrane protein HasF (inferred from 95% identity to pct:PC1_1557)

Predicted SEED Role

"ABC-type protease exporter, outer membrane component PrtF/AprF" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (455 amino acids)

>HER17_RS13205 TolC family outer membrane protein (Pectobacterium carotovorum WPP14)
MQRIAIIVLFGLLSSGANALGLLDAWELALRNDAQFRAAGFEHAAGQEEETIGRANLLPN
LQYGYNANRSHSKVTQTDSFTGNTLKRNYDSYTSTLSLRQPLLDYAAWARYQQGVARTLM
ADQRFRDRSQDLMVRLYQAWSSALLAQEKLQLLDAQQRAYREQLALNKRLLLAGEGTLTD
VRETEARFTLIEAQRIEQQDNLDAAITDLENMTGTALDITTLYPLALTQPPSAESGKQTL
AQWRDLAVQHNAKLATQREGLAVSRYEIERSRAGHLPTLSLVASSRNSRSESEYNYNQKY
DTQSVGLQLNVPLYAGGSVSASMRQAAAEYQQSQAELDDQTKQTLAELKKYYNLYNNGSA
KIKAWQMTASSAQEAVNATRLSVAGGERINLDILLAEQDWYNARRELAEAKYSWLQAWLL
LRYTAGTLNEKDILELAAWFQPATASLANHKIGRN