Protein Info for HER17_RS12935 in Pectobacterium carotovorum WPP14

Annotation: microcin C ABC transporter ATP-binding protein YejF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 538 PF00005: ABC_tran" amino acids 27 to 186 (160 residues), 104.4 bits, see alignment E=2.5e-33 amino acids 303 to 454 (152 residues), 119.9 bits, see alignment E=4e-38 PF08352: oligo_HPY" amino acids 237 to 265 (29 residues), 21.9 bits, see alignment (E = 5.4e-08)

Best Hits

Swiss-Prot: 72% identical to YEJF_ECOLI: Uncharacterized ABC transporter ATP-binding protein YejF (yejF) from Escherichia coli (strain K12)

KEGG orthology group: K13896, microcin C transport system ATP-binding protein (inferred from 98% identity to pct:PC1_1642)

MetaCyc: 72% identical to putative oligopeptide ABC transporter ATP binding subunit YejF (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]

Predicted SEED Role

"Putative ABC transporter ATP-binding protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (538 amino acids)

>HER17_RS12935 microcin C ABC transporter ATP-binding protein YejF (Pectobacterium carotovorum WPP14)
MSSSPLLQIDNLSIAFRKGDQEQRVVDQLSLAVNAGETLALVGESGSGKSVTALSVLRLL
PSPPVVYPQGDIRFAGQSLLHADEKTLRQIRGNRIAMIFQEPMVSLNPLQSIEKQLIEVL
SLHRGMRTEAARSEVITCLDRVGIRQAKSRLNDFPHQLSGGERQRVMIAMALLTQPDLLI
ADEPTTALDVTVQAQILKLLNELKQELGMSLLFITHNLNIVRQLADNVSVMKAGQAVEHN
SCQQLFSAPQHPYTRQLLDAEPSGEPLPVTDDGEPLLRVEKLHVSFPIKRGLLRRTVDEK
QVVNNINFTLRRGESLGLVGESGSGKSTTGLALLRLIQSRGDIWFDGQPLQGLTRKQMLP
FRHRIQVVFQDPNSALNPRLNVEQIIAEGLTVHHKLSKEALDQRVIEAMQEVGLDPTTRY
RYPSEFSGGQRQRIAIARALILQPELLILDEPTSSLDRTVQAQILALLKSLQEKHKIAYL
FISHDLQVIRSLCHQVIVLRQGEVVEQGECKQVFAHPAEHYTRELLQFSSYTAETQSA