Protein Info for HER17_RS12565 in Pectobacterium carotovorum WPP14

Annotation: glutathione S-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 transmembrane" amino acids 100 to 115 (16 residues), see Phobius details PF02798: GST_N" amino acids 3 to 74 (72 residues), 42.6 bits, see alignment E=1.3e-14 PF13417: GST_N_3" amino acids 9 to 79 (71 residues), 42.6 bits, see alignment E=1.2e-14 PF13409: GST_N_2" amino acids 10 to 76 (67 residues), 46 bits, see alignment E=1.3e-15 PF00043: GST_C" amino acids 118 to 194 (77 residues), 34.3 bits, see alignment E=4.8e-12

Best Hits

Swiss-Prot: 56% identical to GSTB_ECOL6: Glutathione S-transferase GstB (gstB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 96% identity to pct:PC1_1679)

MetaCyc: 56% identical to glutathione S-transferase GstB (Escherichia coli K-12 substr. MG1655)
RXN0-6549

Predicted SEED Role

"Uncharacterized glutathione S-transferase-like protein" in subsystem Glutathione: Non-redox reactions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>HER17_RS12565 glutathione S-transferase (Pectobacterium carotovorum WPP14)
MITIWGRDNSTNVKKVLWCAEELALPYQHIAAGRQFGLNHEADYLAMNPNGLIPCLRDGD
LVLWESNTIVRYLAAQYGQDSLYIADAGKRASAEKWMDWATSFAVSFGPVFINMVRVAPE
KRDMALVQKGIAECERLFDIVDTVLANQPWLSGEQFGVGDIPLGCIAYGWLNMPIEQQSH
PHLERWYQQLTERPAYQKHVMIPLS