Protein Info for HER17_RS12555 in Pectobacterium carotovorum WPP14

Annotation: methionine ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 PF00005: ABC_tran" amino acids 22 to 170 (149 residues), 131.9 bits, see alignment E=4e-42 PF09383: NIL" amino acids 261 to 335 (75 residues), 65.4 bits, see alignment E=5.2e-22

Best Hits

Swiss-Prot: 96% identical to METN2_PECAS: Methionine import ATP-binding protein MetN 2 (metN2) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K02071, D-methionine transport system ATP-binding protein (inferred from 96% identity to pct:PC1_1681)

Predicted SEED Role

"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (338 amino acids)

>HER17_RS12555 methionine ABC transporter ATP-binding protein (Pectobacterium carotovorum WPP14)
MIQLEGVSVDFSQGKQPENLAVDNVSLHIQRGEVYGIVGTSGAGKSTLLRTINLLQRPTA
GRVLVNGVLISELAGQPLREQRQKIGMIFQHFNLMQTRTVAENVALSLKAAGKSSADIAA
RVPEILNLVGLTDKALSYPAQLSGGQKQRVGIARAIANDPEVLLCDEPTSALDLETSAAI
LALLKEINEKLGITIVLISHEMSVIKAVCDRVAVMTGGRVVEEGDVFDIFATPQHAFTRQ
LVSHTLDLALPPRLLVDLQGTLLKILFVGESAEQPVLSDVATRFGVSVNILHGKIEYIGN
RALGILVALLTHPSDPGKVTEAVEHIQVRTANVEVLHG