Protein Info for HER17_RS09945 in Pectobacterium carotovorum WPP14
Annotation: o-succinylbenzoate synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 47% identical to MENC_BACSU: o-succinylbenzoate synthase (menC) from Bacillus subtilis (strain 168)
KEGG orthology group: K02549, O-succinylbenzoate synthase [EC: 4.2.1.113] (inferred from 98% identity to pct:PC1_2219)MetaCyc: 47% identical to o-succinylbenzoate synthase (Bacillus subtilis)
o-succinylbenzoate synthase. [EC: 4.2.1.113]
Predicted SEED Role
"O-succinylbenzoate synthase (EC 4.2.1.113)" (EC 4.2.1.113)
MetaCyc Pathways
- superpathway of chorismate metabolism (53/59 steps found)
- superpathway of menaquinol-8 biosynthesis I (10/10 steps found)
- superpathway of demethylmenaquinol-8 biosynthesis I (9/9 steps found)
- 2-carboxy-1,4-naphthoquinol biosynthesis (7/7 steps found)
- superpathway of menaquinol-10 biosynthesis (9/10 steps found)
- superpathway of menaquinol-11 biosynthesis (9/10 steps found)
- superpathway of menaquinol-12 biosynthesis (9/10 steps found)
- superpathway of menaquinol-13 biosynthesis (9/10 steps found)
- superpathway of menaquinol-6 biosynthesis (9/10 steps found)
- superpathway of menaquinol-7 biosynthesis (9/10 steps found)
- superpathway of menaquinol-9 biosynthesis (9/10 steps found)
- superpathway of demethylmenaquinol-6 biosynthesis I (8/9 steps found)
- superpathway of demethylmenaquinol-9 biosynthesis (8/9 steps found)
- superpathway of phylloquinol biosynthesis (7/15 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 4.2.1.113
Use Curated BLAST to search for 4.2.1.113
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (370 amino acids)
>HER17_RS09945 o-succinylbenzoate synthase (Pectobacterium carotovorum WPP14) MKIDKIVLRKMKMALKTPFTTSFATQTEKHFSIAEVHAGGQIGYGDCSAISLPFYNEETN VTAWHIMRDFLIPMIKQAGDIEHPSQVRDIFAPVKRNNCAKAAIEGGIWDAYAKIKGVPL HQLLGGVRNNVEAGVSIGIQDTPDQLVSVVDNFLNEGYKRIKIKIKPGKDYDYIAALRQT FGDITLMVDANSAYTLDDIDFFKRIDKFNLLMIEQPLAHDDIIDHRKLQAAVNTPICLDE SIASVEDARKAIELGSAKIINIKVARVGGITETKLIHDYCQAHNIPVWCGGMLDTAVGKA HNIAVSTLPNFIYAHDIPPSSRYWHEDFMLPFVELDKDSCVAVPNKPGIGFDINPELYEK YCYGQETFLF