Protein Info for HER17_RS09815 in Pectobacterium carotovorum WPP14

Annotation: ornithine cyclodeaminase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02423: OCD_Mu_crystall
  • amino acids 12 to 299 (288 residues), 196.9 bits, E=4.1e-62
• PF01488: Shikimate_DH
  • amino acids 128 to 211 (84 residues), 32.1 bits, E=1.1e-11

Best Hits

KEGG orthology group: K01750, ornithine cyclodeaminase [EC: 4.3.1.12] (inferred from 94% identity to pct:PC1_2251)

Predicted SEED Role

"Ornithine cyclodeaminase (EC 4.3.1.12)" in subsystem Arginine and Ornithine Degradation (EC 4.3.1.12)

MetaCyc Pathways

• L-ornithine degradation I (L-proline biosynthesis) (1/1 steps found)
• L-arginine degradation VII (arginase 3 pathway) (1/2 steps found)
• L-proline biosynthesis II (from arginine) (1/2 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.3.1.12

Protein Sequence (313 amino acids)

>HER17_RS09815 ornithine cyclodeaminase family protein (Pectobacterium carotovorum WPP14)
MIFISESESAELINHELAYDAVREALLAASEPEARSFPVVHGQGSDPVNTFSIKASATSE
LAGLKVGSFWPGNPANGLPRHNSLILLFEQQIGKIAVAIEAGKVNAFRTAAANAVAADLL
ARPDASVLAVFGTGHQARYECAALARIRPIRTVLIVGRDSSKSTDMARELQAAGLDAQIS
DAESACRAADIIVTATPSRAPLFNAEWVNAGTHVVSMGSDAVGKQELPPELFTTGRLFCD
LPSQSRMIGDFQHAPAHVMLTAIGDVISASAAGRQTQDDITVFDSSGLSIQDLYIGQRIL
AAWQQAKRNEGAQ