Protein Info for HER17_RS09730 in Pectobacterium carotovorum WPP14

Annotation: C4-dicarboxylic acid transporter DauA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 567 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 100 to 120 (21 residues), see Phobius details amino acids 130 to 151 (22 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 280 to 303 (24 residues), see Phobius details amino acids 323 to 343 (21 residues), see Phobius details amino acids 350 to 369 (20 residues), see Phobius details amino acids 375 to 392 (18 residues), see Phobius details amino acids 412 to 441 (30 residues), see Phobius details TIGR00815: sulfate permease" amino acids 18 to 558 (541 residues), 452.3 bits, see alignment E=1.1e-139 PF00916: Sulfate_transp" amino acids 29 to 414 (386 residues), 282.8 bits, see alignment E=3.8e-88 PF01740: STAS" amino acids 458 to 557 (100 residues), 49.4 bits, see alignment E=3.4e-17

Best Hits

Swiss-Prot: 76% identical to DAUA_ECOLI: C4-dicarboxylic acid transporter DauA (dauA) from Escherichia coli (strain K12)

KEGG orthology group: K03321, sulfate permease, SulP family (inferred from 99% identity to pct:PC1_2268)

MetaCyc: 76% identical to aerobic C4-dicarboxylate transporter DauA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-122A; TRANS-RXN0-553

Predicted SEED Role

"Putative sulfate permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (567 amino acids)

>HER17_RS09730 C4-dicarboxylic acid transporter DauA (Pectobacterium carotovorum WPP14)
MKTHGINGVRPFSALIDACWREKYTLQRFTHDIIAGVTVGIIAIPLAMALAIASGVPPQY
GLYTSAIAGIVIAVSGGSRYSVSGPTAAFVVILYPVSQQFGLSGLLVATLLSGVFLLLMG
LCRFGRLIEYIPLSVTLGFTSGIAITIGTMQIKDFFGLQMAVVPEHYVEKVAALAQSLPT
LHLADTLIGATTLLVLIVWPRLGIRLPGHLPALLAGVAVMGIMSLLGENVATIGSRFSYM
LADGSQGQGIPPILPQLILPWDIPSPDGKTMTLDWQSISALLPAAFSMAMLGAIESLLCA
VVLDGMTGKKHNSNAELMGQGFGNIIAPFFGGITATAAIARSAANVRAGANSPISAVIHA
LLVLLALLILAPWLSYLPLAAMASLLLIVAWNMSEAHKVVDLLRHGPKDDIIVMLLCMSL
TVLFDMVIAITVGIVLASLLFMRRIAQMTRLSELPDTKIPDHLVLRVNGPLFFAAAERIF
NELTVRSEGYQNIILQWDAVPVLDAGGLNAFLRFSETLPEGKQLIITDIPFQPLKTLARA
KVHPIEGRLSFYGSLAQAIEATTVRSA