Protein Info for HER17_RS08770 in Pectobacterium carotovorum WPP14

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00106: adh_short" amino acids 4 to 184 (181 residues), 163.8 bits, see alignment E=9e-52 PF08659: KR" amino acids 6 to 156 (151 residues), 34.9 bits, see alignment E=3.8e-12 PF01370: Epimerase" amino acids 6 to 116 (111 residues), 33.6 bits, see alignment E=6.9e-12 PF13460: NAD_binding_10" amino acids 10 to 181 (172 residues), 28.5 bits, see alignment E=3.4e-10 PF13561: adh_short_C2" amino acids 10 to 188 (179 residues), 123.8 bits, see alignment E=2.3e-39

Best Hits

KEGG orthology group: None (inferred from 88% identity to pct:PC1_2479)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (279 amino acids)

>HER17_RS08770 oxidoreductase (Pectobacterium carotovorum WPP14)
MKSKVILVTGASSGIGEAAALRLKASGHTVYAAARRIERMQKLAEVGIRVLPLDVTDSVS
VQTVVDTIIAECGRIDVVVNNAGYGSYGAVEEVSPEEGRAQFDVNVFGAVRLTQLVLPHM
RAQRSGTVINITSMGGKIYTPLGAWYHGTKFALEAISDCLRLEVEPFGVDVVVIEPGGIK
TEWADIAAAKLLDVSGHGAYAKQAEAMADSMVGDSSRKRQSSPQVIADTIAQAVNARRPK
TRYAVGFGAKPMICLRRLLSDRLFDRFMRMATGISRHSQ