Protein Info for HER17_RS08570 in Pectobacterium carotovorum WPP14

Annotation: rhodanese-related sulfurtransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 355 PF17773: UPF0176_N" amino acids 25 to 117 (93 residues), 74.2 bits, see alignment E=1.3e-24 PF00581: Rhodanese" amino acids 138 to 232 (95 residues), 58 bits, see alignment E=1.7e-19 PF12368: Rhodanese_C" amino acids 246 to 308 (63 residues), 79.6 bits, see alignment E=2.6e-26

Best Hits

Swiss-Prot: 96% identical to Y1781_PECAS: UPF0176 protein ECA1781 (ECA1781) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K07146, UPF0176 protein (inferred from 97% identity to pct:PC1_2519)

MetaCyc: 73% identical to tRNA U34 hydroxylase TrhO (Escherichia coli K-12 substr. MG1655)
RXN0-7349

Predicted SEED Role

"Rhodanese domain protein, Enterobacterial subgroup, YceA homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (355 amino acids)

>HER17_RS08570 rhodanese-related sulfurtransferase (Pectobacterium carotovorum WPP14)
MPVLHNRISNEELKARMLAETEPRTTVSFYKYFTIDDPKAFRDCLYIQLEQYKVFGRIYI
ATEGINAQISVPNNQFDAFKAALFSAHPALDQIRLNIALEDDGKSFWVLRMKVRERIVAD
GIDDPTFNPANVGQYLKADQVNAMADDPDTVFVDMRNHYEYEVGHFENALEVPSDTFREQ
LPMAVEMLDEVRDKNIVMYCTGGIRCEKASAYMLHHGFKNVYHVEGGIIEYTRQAKAQGL
PLKFIGKNFVFDERMGERISDDVIAHCHQCGASCDSHTNCRNEGCHLLFIQCPSCAAKYE
GCCSTQCQDETKLPLEEQRAIRSGRENGMKIFNKSKGLLQSTLHIPAPVAKDKAE