Protein Info for HER17_RS08410 in Pectobacterium carotovorum WPP14

Annotation: Lon protease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 589 PF13654: AAA_32" amino acids 149 to 237 (89 residues), 47.9 bits, see alignment E=1.4e-16 PF05362: Lon_C" amino acids 447 to 549 (103 residues), 37.3 bits, see alignment E=2.2e-13

Best Hits

KEGG orthology group: K04770, Lon-like ATP-dependent protease [EC: 3.4.21.-] (inferred from 97% identity to pct:PC1_2551)

Predicted SEED Role

"Putative protease La homolog (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (589 amino acids)

>HER17_RS08410 Lon protease family protein (Pectobacterium carotovorum WPP14)
MYNHAFPSDDYIDTLTSNRLSWQHLLPNNTPYHTLFTQAAQLAPAEFSAIQSRLADSLTL
FCHPRSPSRFMLLKAQENDEYMALIARALSAIRPDSGAIHGSKYIIEGRHIRVEPATQPA
DNFAAQQSCGYQEWIEPEQLFGCVRSFHDEVTLHPGLIHQVNGGTLILSARALLAQPLMW
LRLKQIMAEGIYRWLSPDERKPLPVDVPPMPLDVRLIILGDRESLADIHDMEPELGEHAI
YGEFEAQLQLIETDDMARWCSYINALCSENQLPLLDADAWPALVNVAIRYSGDQGNLPLC
PRWLIGQLKYASLYARDGQITEQALVDAVAARQWREGYLRERMQDEIELGQILIETEGEV
VGQINGLSVLEFPGYPVAFGEPTRISCVVHAGDGEFTDVERKAELAGNLHAKGMMIMQAF
LITELELDQQLPFSASIVFEQSYSEVDGDSASLAELCALVSALSLRPINQQFAVTGSVDQ
FGHVQPIGGVNEKIEGFFEVCQRRGLTGTQGVILPAANLRHLCLQEDVVEAVREGKFHLF
PVETAPEALSLLTNLAYDDEQQPNLLSAIRERIGQLAPQERRRFPWFFR