Protein Info for HER17_RS07535 in Pectobacterium carotovorum WPP14

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 44 to 356 (313 residues), 195.2 bits, see alignment E=6.8e-62 PF16576: HlyD_D23" amino acids 59 to 261 (203 residues), 45.4 bits, see alignment E=1.2e-15 PF13533: Biotin_lipoyl_2" amino acids 67 to 107 (41 residues), 24.7 bits, see alignment 3.3e-09 PF13437: HlyD_3" amino acids 172 to 263 (92 residues), 36.2 bits, see alignment E=1.7e-12

Best Hits

KEGG orthology group: None (inferred from 82% identity to rah:Rahaq_1908)

Predicted SEED Role

"RND efflux membrane fusion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (369 amino acids)

>HER17_RS07535 efflux RND transporter periplasmic adaptor subunit (Pectobacterium carotovorum WPP14)
MLRLKSATLAVCLLPLALVACGDATNVDDPRNQPPLVRTATVVSAAETSRSFTGVVVART
QSDLGFRVQGKILERLVDTGESVKRGQPLMRLDPIDLSLQAQAQQQTVAAARARARQATD
DEARYRGLVAAGAISASAYDQIKAAAETAKAELSATQAQADVARNATGYAVLMADADGVV
VDTLAEPGQVVSAGQPVIRLARAGQREAVVHLPETLRPVVGSEAMAMRYGSGNPAIPVKL
RLLSDAADSQTRTFEARYVLEGALANAPLGSTVTLNIAEDKLSDPVLQVPIAALYDAGKG
PGVWSISGEPIKVSWHPVNVLGLGDDTARVTGGLQPGEQIVALGAHLLHEGEEIRMAESR
AADTAGNRP