Protein Info for HER17_RS06540 in Pectobacterium carotovorum WPP14

Annotation: lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 84 to 109 (26 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 143 to 153 (11 residues), see Phobius details amino acids 166 to 195 (30 residues), see Phobius details amino acids 207 to 228 (22 residues), see Phobius details amino acids 260 to 282 (23 residues), see Phobius details amino acids 294 to 312 (19 residues), see Phobius details amino acids 318 to 340 (23 residues), see Phobius details amino acids 352 to 378 (27 residues), see Phobius details amino acids 384 to 403 (20 residues), see Phobius details amino acids 410 to 431 (22 residues), see Phobius details PF02366: PMT" amino acids 12 to 240 (229 residues), 123.9 bits, see alignment E=8.4e-40 PF13231: PMT_2" amino acids 64 to 225 (162 residues), 41.7 bits, see alignment E=1.5e-14

Best Hits

Swiss-Prot: 94% identical to ARNT_PECCP: Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase (arnT) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K07264, 4-amino-4-deoxy-L-arabinose transferase [EC: 2.-.-.-] (inferred from 94% identity to pct:PC1_2924)

Predicted SEED Role

"Polymyxin resistance protein ArnT, undecaprenyl phosphate-alpha-L-Ara4N transferase; Melittin resistance protein PqaB"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.-.-.-

Use Curated BLAST to search for 2.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (556 amino acids)

>HER17_RS06540 lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase (Pectobacterium carotovorum WPP14)
MEKGMIRLKSTMILVLFALLYLLPLNGRWLWSPDETRYAEISREMLQRGDWIVPHLLGIR
YFEKPVAGYWLNNISQWLLGHTNFAVRFASVFSTGLSALLVFWLAMLLWKNQRTALLAAT
IYLTSLFVYGIGTYSVLDPMVTLWMTAALFSHVLILRATLTRERLVAWGLMGLACGMGFM
TKGFLALALPVISVLPVALAQKRIKELLLFGPLAIVVAVLLSAPWALAVHAREADYWHYF
FWIEHIQRFAEDDAQHKAPFWYYLPVLILGAFPWLALLPGALRSGWTERKAYPERFLLLC
WMVMPLLFFSIAKGKLLTYILPCFAPLALLMAAWISGLVPAVRERVLRINSWLNIAFGSV
LALAVAALGLGIIVPHFYQSGEGLTIVSGVVCFIGWVAFAAVSLKKQRTWGYLVAGCPLF
LALLVGGSIPASVVDSKNPQTFIRSHQPLLEDSRYVLSDEVGLAAGLAWELKRSDITLFK
ARGELNYGLNYADSADRFVDEGAFPTWLAEKRRSGNVALMLKIDRDSDDEYRNLPAPDQL
RKSHRYVLLFYKQVAP