Protein Info for HER17_RS04660 in Pectobacterium carotovorum WPP14

Annotation: SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 PF00891: Methyltransf_2" amino acids 16 to 190 (175 residues), 29.8 bits, see alignment E=2.5e-10 PF01209: Ubie_methyltran" amino acids 26 to 159 (134 residues), 73.9 bits, see alignment E=8.7e-24 PF13489: Methyltransf_23" amino acids 36 to 192 (157 residues), 65 bits, see alignment E=4.7e-21 PF05175: MTS" amino acids 45 to 170 (126 residues), 33.8 bits, see alignment E=1.7e-11 PF07021: MetW" amino acids 45 to 138 (94 residues), 22.5 bits, see alignment E=5.3e-08 PF05148: Methyltransf_8" amino acids 46 to 167 (122 residues), 28.1 bits, see alignment E=1.2e-09 PF03848: TehB" amino acids 46 to 148 (103 residues), 23 bits, see alignment E=3.3e-08 PF06325: PrmA" amino acids 46 to 149 (104 residues), 23.9 bits, see alignment E=1.8e-08 PF13847: Methyltransf_31" amino acids 47 to 171 (125 residues), 88.5 bits, see alignment E=2.5e-28 PF03141: Methyltransf_29" amino acids 48 to 146 (99 residues), 23.1 bits, see alignment E=1.8e-08 PF13649: Methyltransf_25" amino acids 49 to 142 (94 residues), 87.8 bits, see alignment E=4.2e-28 PF08242: Methyltransf_12" amino acids 50 to 144 (95 residues), 62.7 bits, see alignment E=2.9e-20 PF08241: Methyltransf_11" amino acids 51 to 146 (96 residues), 96.3 bits, see alignment E=9e-31

Best Hits

KEGG orthology group: None (inferred from 94% identity to pct:PC1_3293)

Predicted SEED Role

"SAM-dependent methyltransferase YafE (UbiE paralog)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>HER17_RS04660 SAM-dependent methyltransferase (Pectobacterium carotovorum WPP14)
MEEKQNHNHRVEHQFGSQAQNYLTSAVHAQGKDLTRLAALLAPFPQARVIDLGCGAGHAS
FVAAQAVAEVVAYDLSSQMLDVVSQAAAEKGLHNIRVQQGVAESLPFEDSSADIIISRYS
AHHWHDVGQALREMRRVLKPGGRVIMMDVVSPGHPLLDSYLQTVEKLRDTSHVRNYAPGE
WLSLFTDAGFIVRNVTSDRLTLEFSSWIARMRTPEHFAVAIRELQKTLPDEVVQHFEVQA
DGSFVTDIMMIEATRA