Protein Info for HER17_RS03830 in Pectobacterium carotovorum WPP14
Annotation: nitric oxide-sensing transcriptional repressor NsrR
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 99% identical to NSRR_PECCP: HTH-type transcriptional repressor NsrR (nsrR) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)
KEGG orthology group: K13771, Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor (inferred from 99% identity to eca:ECA3623)Predicted SEED Role
"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (141 amino acids)
>HER17_RS03830 nitric oxide-sensing transcriptional repressor NsrR (Pectobacterium carotovorum WPP14) MQLTSFTDYGLRALIYMASLPGGKMTSISEVTEVYGVSRNHMVKIINQLSRAGLVMAVRG KNGGIRLGKPAETIRIGDVVRELEPLTLVNCSHEFCHITPACRLKQVLQQAVQNFLHELD QYTLADMVKENPPLYKLLLVE