Protein Info for HER17_RS00785 in Pectobacterium carotovorum WPP14

Annotation: agmatine deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03380: agmatine deiminase
  • amino acids 10 to 365 (356 residues), 568.6 bits, E=2.4e-175
• PF04371: PAD_porph
  • amino acids 19 to 364 (346 residues), 410.7 bits, E=2.3e-127

Best Hits

Swiss-Prot: 95% identical to AGUA_PECAS: Putative agmatine deiminase (aguA) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K10536, agmatine deiminase [EC: 3.5.3.12] (inferred from 94% identity to pwa:Pecwa_0168)

Predicted SEED Role

"Agmatine deiminase (EC 3.5.3.12)" in subsystem Arginine and Ornithine Degradation or Polyamine Metabolism (EC 3.5.3.12)

MetaCyc Pathways

• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (3/3 steps found)
• putrescine biosynthesis II (3/3 steps found)
• superpathway of polyamine biosynthesis II (6/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.12

Protein Sequence (367 amino acids)

>HER17_RS00785 agmatine deiminase (Pectobacterium carotovorum WPP14)
MPQLATPQITTPQQDGFAMPAEWAPHDAVWMIWPYRTDNWREQGVPAQKTFARVAEAIAQ
NTPVIMGVPARYMADAQKVMPVNVTLVEMESDDAWMRDTGPTIVLNQAGERRGIDWQFNA
WGGELGGLYEDWRQDEKVAAQVLDYHQAARYVAPLILEGGSIHVDGEGTLLTTAECLLNP
NRNPHLSKAEIEQLMRDYLDISTVIWLEEGVYNDETDGHIDNMCCFVRPGEVALHWTDDE
NDPQYVRSMAAYRVLSTAKDAQGRQLKIWKLPAPGPLYATKEEAQGVDSGDAVERLAGSR
LAGSYVNFLISNQQIIFPLLDEKTDDVARDLLQQMFPGYLISGVPAREILLGGGNIHCIT
QQIPATK