Protein Info for HER17_RS00480 in Pectobacterium carotovorum WPP14

Annotation: permease-like cell division protein FtsX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 transmembrane" amino acids 42 to 65 (24 residues), see Phobius details amino acids 185 to 212 (28 residues), see Phobius details amino acids 238 to 264 (27 residues), see Phobius details amino acids 270 to 288 (19 residues), see Phobius details amino acids 294 to 313 (20 residues), see Phobius details TIGR00439: putative protein insertion permease FtsX" amino acids 23 to 321 (299 residues), 418.8 bits, see alignment E=6.3e-130 PF18075: FtsX_ECD" amino acids 80 to 174 (95 residues), 55.2 bits, see alignment E=8.7e-19 PF02687: FtsX" amino acids 197 to 311 (115 residues), 48.4 bits, see alignment E=9.1e-17

Best Hits

Swiss-Prot: 71% identical to FTSX_ECOL6: Cell division protein FtsX (ftsX) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K09811, cell division transport system permease protein (inferred from 99% identity to pwa:Pecwa_0095)

Predicted SEED Role

"Cell division protein FtsX" in subsystem Bacterial Cell Division

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (322 amino acids)

>HER17_RS00480 permease-like cell division protein FtsX (Pectobacterium carotovorum WPP14)
MANNVRNAKKPVAKAKALRGGWQEQWRYAWTNTLADMLRQPLATFLTVMVIAISLALPSI
CYLVWKNVSQAATQWYPSPQLTVYLDKSLDDNAAQAVITQLQSEDGVDKVNYLSRNEAMG
EFRNWSGFGGALDMLEENPLPAVAIITPKMSFQDSTTLTTLRDRVAATQGVDEVRMDDSW
FARLVALTNLVGQISATIGVLMVVAVFLVIGNSVRLSIFSRRETINVMKLIGATDGFILR
PFLNGGAAMGVGGAVLSLILSQALVWKLDAVVAQVASVFGTTFAVKGLSWDESLLLLLIA
GMIGWLAAWLATVQHLRRFTPQ