Protein Info for HER17_RS00420 in Pectobacterium carotovorum WPP14

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 49 to 66 (18 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 112 to 141 (30 residues), see Phobius details amino acids 153 to 174 (22 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details amino acids 221 to 247 (27 residues), see Phobius details amino acids 253 to 272 (20 residues), see Phobius details amino acids 284 to 302 (19 residues), see Phobius details amino acids 311 to 331 (21 residues), see Phobius details amino acids 343 to 367 (25 residues), see Phobius details amino acids 372 to 391 (20 residues), see Phobius details PF07690: MFS_1" amino acids 27 to 271 (245 residues), 70.4 bits, see alignment E=7e-24 amino acids 255 to 391 (137 residues), 40.2 bits, see alignment E=1.1e-14

Best Hits

Swiss-Prot: 71% identical to YHHS_ECOLI: Uncharacterized MFS-type transporter YhhS (yhhS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to pwa:Pecwa_0084)

Predicted SEED Role

"Transporter, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (398 amino acids)

>HER17_RS00420 MFS transporter (Pectobacterium carotovorum WPP14)
MPTPSPSEPSLSGLRLNLRIVSIVAFNFASYLNIGLPLAVLPGYVHDHLGYSAFWAGLVI
SLQYFSTLVSRPHAGRSADEKGPKKIVVWGLAGVMLSGVFYLLAAFSDASPVITLLLLCL
GRIVLGAGQSFAGTGATLWGVGVVGSRHIGRVISWNGIATYGAMAIGAPLGVWLNHIGGL
KLLSVCIILIAAVAIVLALPRPAVQVAPGKKIPFREVLGKVWVYGIILAIASAGFGVIAT
FITLFYADRNWEGAALTLTIFSCAFVGARLVFPNSIQRFGGLRVAMACFVVEIVGLLLVW
GATQPLMAEVGAFLAGAGFSLVFPALGVVAVKAVSPQNQGSALATYTIFLDLSLGIVGPV
AGVLMAYTGIASIYLAAALLGLCGLALTWRLTQRIANV