Protein Info for HEPCGN_14275 in Escherichia coli ECOR38

Annotation: outer membrane beta-barrel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 103 PF13505: OMP_b-brl" amino acids 3 to 103 (101 residues), 41.3 bits, see alignment E=2.9e-14 PF01389: OmpA_membrane" amino acids 12 to 95 (84 residues), 22.6 bits, see alignment E=1.2e-08 PF02530: Porin_2" amino acids 27 to 98 (72 residues), 25.8 bits, see alignment E=1.1e-09

Best Hits

Predicted SEED Role

"Peptide transport periplasmic protein sapA (TC 3.A.1.5.5)" in subsystem ABC transporter peptide (TC 3.A.1.5.5) (TC 3.A.1.5.5)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (103 amino acids)

>HEPCGN_14275 outer membrane beta-barrel protein (Escherichia coli ECOR38)
VSVGLGYARIHHKATYTDTSWNKSGEVSDISALHYSGYDNNFAWSIGAGVRYDITPDIAL
DLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDIMFGVTYNF