Protein Info for GFF997 in Xanthobacter sp. DMC5

Annotation: Magnesium-transporting ATPase, P-type 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 875 transmembrane" amino acids 84 to 117 (34 residues), see Phobius details amino acids 227 to 246 (20 residues), see Phobius details amino acids 260 to 284 (25 residues), see Phobius details amino acids 292 to 316 (25 residues), see Phobius details amino acids 684 to 707 (24 residues), see Phobius details amino acids 742 to 766 (25 residues), see Phobius details amino acids 776 to 794 (19 residues), see Phobius details amino acids 806 to 857 (52 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 29 to 95 (67 residues), 47.6 bits, see alignment 2.1e-16 TIGR01524: magnesium-translocating P-type ATPase" amino acids 36 to 860 (825 residues), 717.5 bits, see alignment E=2e-219 PF00122: E1-E2_ATPase" amino acids 138 to 325 (188 residues), 141 bits, see alignment E=6.4e-45 TIGR01494: HAD ATPase, P-type, family IC" amino acids 239 to 379 (141 residues), 67.4 bits, see alignment E=8.2e-23 amino acids 584 to 702 (119 residues), 84.8 bits, see alignment E=4.5e-28 PF00702: Hydrolase" amino acids 343 to 628 (286 residues), 47.4 bits, see alignment E=6.2e-16 PF00689: Cation_ATPase_C" amino acids 697 to 860 (164 residues), 70.3 bits, see alignment E=3.6e-23

Best Hits

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 62% identity to gdj:Gdia_2384)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (875 amino acids)

>GFF997 Magnesium-transporting ATPase, P-type 1 (Xanthobacter sp. DMC5)
MKGLLYRAVFVRRVSAPNGNGAPEAAAFWTEAPAALCHRLGCGTAGLSQGEAAERLEHFG
PNLDKPPSRTTPVRALLRRLLEPLMLMLLVAAGVSAATGDAASAVIIILVIVASIGLDTV
QEARASKAAAALREQVALTAEVCRDGVFATLPTDRIVPGDVFRVRTGDIIPADAVILSAD
GFSANEAALTGEPYAVEKRPGAVSSTVAAEATNALFRGAVAQSGEAVALAVATGKGTLFG
AAAALLAEDAGLSPFQRDLRALGFVIARAAGVLSVAVLAVNLVLGRPLLESLMFAVALAV
GLTPELLPMITTVTLSRGAVRMAQRKVIVKRLTAIHDLGAMTVLCTDKTGTLTSAEIVLA
ASEDGGGQAAHRPAELAALCAELAGDRSWMDTALAAAAPAAADGWSAPSRLGFGYERRRG
SVLAERAGEGIAERLLVCKGAPEAVMDVCTCRRVGDAIVELDAEARSALAAQLKRYAEQG
LRAIAVATRAGTPDGMARTGSLEPEDESGLVLEGFCLFEDPPKPTAAHALTRLAAAGVRV
KVLSGDDPTVVAHVAGQLGIDAADMLSGAEVAHLSDDALRVRVRSVNVFGRMTPNQKVRV
VRALMANGETVGFLGDGVNDAPGLKLADVGLSVDGATGVARAAADMILLAPDLDVVADGV
EEGRRTFANILKYVRMGASSNFGNMLSMAAASLFLPFLPLLATQILLNNLLYDLSEVGIP
FDAVDEADLATPQQWDMKGLVRFAAVMGPLSSVFDFLTFGVLLLVLNTGVEAFRTAWFLE
SIATQVLVVFLIRTRLPLGETPPDRTLIISALGALAVAFVVPLSGVGGWFGFVPLPATTL
LAVAGITLAYLFCAEGVKHFAVGGPRPRGRAGTEG