Protein Info for GFF980 in Sphingobium sp. HT1-2

Annotation: Sulfur acceptor protein => iron-sulfur cluster assembly SufE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF02657: SufE" amino acids 23 to 138 (116 residues), 111.7 bits, see alignment E=9.7e-37

Best Hits

Swiss-Prot: 32% identical to SUFE_YERP3: Cysteine desulfuration protein SufE (sufE) from Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)

KEGG orthology group: K02426, cysteine desulfuration protein SufE (inferred from 90% identity to sjp:SJA_C1-34060)

Predicted SEED Role

"Sulfur acceptor protein SufE for iron-sulfur cluster assembly"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (144 amino acids)

>GFF980 Sulfur acceptor protein => iron-sulfur cluster assembly SufE (Sphingobium sp. HT1-2)
MGGMTDQPAPMPVLADLQEEYEFLDADDRYRLLIDLGRGLEDMPDALKTDMTLVRGCSAA
VWVYPTVLDDGRLHFLADSNAAITKGIIALVLLTVQDRAPAEIGATDIEGALAPFDLKNQ
LSSNRTQGIPNMIALIRETAARYA